


Randomised Controlled Trial Comparing the Safety and EfficAcy of the Cocoon PFO Occluder versus Amplatzer PFO ClosurE Device for Percutaneous Closure of Patent Foramen Ovale in Patients with a History of Stroke or Transient Ischemic Attack
A Non-profit, Single-blind, Investigator Driven Trial
Trial was registered at Clinicaltrials.gov under NCT07380490
STUDY TEAM
Meet the dedicated experts leading the SAFE-PFO trial, including the Sponsor, Principal Investigators and Steering Committee, working together to ensure scientific excellence and patient safety
Sponsor

Prof. Giuseppe Tarantini
Department of Cardiac, Thoracic, and Vascular Sciences, University of Padova, Italy
Adress: Via 8 Febbraio, 2 - 35122 Padova, Italy
Mail: giuseppe.tarantini.1@unipd.it
Principal Investigators



Prof. Gabor G. Toth
Prof. Gilles Montalescot
Prof. Giuseppe Tarantini
PRINCIPAL INVESTIGATOR
Department of Cardiac, Thoracic, and Vascular Sciences, University of Padova, Italy
Co-PRINCIPAL INVESTIGATOR
Paris Sorbonne Université, ACTION Study Group, INSERM UMR_S 1166, Institut de Cardiologie, Pitié-Salpêtrière Hospital (Assistance Publique-Hôpitaux de Paris), Paris, France.
Co-PRINCIPAL INVESTIGATOR
University Heart Center Graz, Medical University of Graz, Austria
Steering Committee Members




Prof. Giuseppe Tarantini
Prof. Gabor G. Toth
Prof. Gilles Montalescot
Prof. Horst Sievert




Prof. Francesco Causin
Dr Suneil Aggarwal
Prof. Claudio Baracchini
Prof. Dario Gregori


Prof. Tadeusz Przewłocki
Dr. Francesco Cardaioli
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CRO TEAM
COORDINATING CRO

Endocorelab srl
Via San Bellino n.44 – 35020 Albignasego (PD) - ITALY
Zeta Reseach srl
Via A. Caccia, 8 - 34129 Trieste
Italia

Action Coeur
Institut de Cardiologie Hôpital Pitié-Salpêtrière 2éme étage 47 boulevard de l’Hôpital 75013 Paris